3,3'-Diethyloxacarbocyanine iodide

Specifications / Handling

More Information
Product Details
Synonyms	DiOC2(3); 3-Ethyl-2-[3-(3-ethyl-2(3H)-benzoxazolylidene)-1-propenyl]benzoxazolium iodide; DOC iodide
Product Type	Chemical
Properties
Formula	C₂₁H₁₉IN₂S
MW	460.31
CAS	905-96-4
Purity Chemicals	≥98% (Titration)
Appearance	Dark red crystals or powder.
Solubility	Soluble in DMSO or methanol.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	FIZZUEJIOKEFFZ-UHFFFAOYSA-M
Smiles	CCN1/C(OC2=CC=CC=C12)=C\C=C\C3=[N+](CC)C4=CC=CC=C4O3.[I-]
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+20°C
Long Term Storage	+20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at RT.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

3,3'-Diethyloxacarbocyanine iodide is a cyanine based dye that has been used for measuring membrane potentials in bacteria. The green fluorescent dye forms red fluorescent aggregates with increasing membrane potential. The spectral shifting phenomenon has been exploited to measure membrane potential and analyze bacterial viability by flow cytometry ratiometrically. Spectral data: λmax 483nm (methanol); λem 498nm (methanol). The dye has also been used as laser dye and in photosensitization of mitochondria and endoplastic recticulum in animals and plant cells. It may be used as a conjugate for labelling cells for cytofluorometry studies and in the imaging of carbon nanotubes(CNTs) using fluorescence microscopy.

Product References

(1) D.N. Dempster, et al.; J. Chem. Soc. Faraday II 68, 1479 (1972) | (2) D. Magde & M.W. Windsor; Chem. Phys. Lett. 27, 31 (1974) | (3) M. Zalokar & C. Sardet; Dev. Biol. 102, 195 (1984) | (4) M. Castedo, et al.; J. Immunol. Meth. 265, 39 (2002) | (5) H.J. Broxterman, et al.; Leukemia 11, 1110 (1997) | (6) D.J. Novo, et al.; Cytometry 35, 55 (1999) | (7) D.J. Novo, et al.; Antimicrob. Agents Chemother. 44, 827 (2000) | (8) D.R. Gentry, et al.; J. Microbiol. Methods 83, 254 (2010) | (9) R.W. Sabnis; Handbook of biological dyes and stains (2010) | (10) M.A. Hudson, et al.; Antimicrob. Agents Chemother. 64, e00910 (2020)

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